The 2021 Copa CONMEBOL Libertadores de Futsal was the 20th edition of the Copa Libertadores de Futsal, South America's premier club futsal tournament organized by CONMEBOL. The tournament was held in Florida, Uruguay between 16 and 22 May 2021.
The tournament was originally scheduled to be played from 1 to 8 May 2021, but was rescheduled from 15 to 22 May at request of the Local Organizing Committee. However, the start date was delayed to 16 May due to problems with the teams' flights and permits to enter the host country.
Carlos Barbosa were the defending champions.
The competition was contested by 12 teams: the title holders, one entry from each of the ten CONMEBOL associations, plus an additional entry from the host association.
The tournament was played at the Polideportivo 10 de Julio in Florida, Uruguay.
The draw of the tournament was held on 27 April 2021, 12:00 UYT (). The draw was conducted based on Regulations Article 16 as follows:
Initially, three teams were seeded and assigned to the head of the groups (Carlos Barbosa automatically to Group A, the others two via a draw from pot 1):
The remaining nine teams were split into three pots of three based on the final placement of their national association's club in the previous edition of the championship, with the highest three (Colombia, Peru and Brazil) placed in Pot 2, the next three (Vanezuela, Argentina and Chile) placed in Pot 3 and the lowest two (Bolivia and Ecuador) in pot 4, alongside the additional Uruguayan club. From each pot, the first team drawn was placed into Group A, the second team drawn placed into Group B and the final team drawn placed into Group C. Clubs from the same association could not be drawn into the same group.
The draw resulted in the following groups:
Each team has to submit a squad of 14 players, including a minimum of two goalkeepers.
The top two teams of each group and the two best third-placed teams advance to the quarter-finals.
The teams are ranked according to points (3 points for a win, 1 point for a draw, 0 points for a loss). If tied on points, tiebreakers are applied in the following order (Regulations Article 21):
All times are local, UYT ().
In the quarter-finals, semi-finals and final, extra time and penalty shoot-out would be used to decide the winner if necessary (no extra time would be used in the play-offs for third to twelfth place).
The quarter-final matchups are:
The semi-final matchups are: