This is a list of players who graduated from the Challenge Tour in 2021. The top 20 players on the Challenge Tour rankings in 2021 earned European Tour cards for 2022.
<nowiki>*</nowiki> European Tour rookie in 2022<br/> <sup>â </sup> First-time full member, but ineligible for Rookie of the Year award<br/> T = Tied<br/> The player retained his European Tour card for 2023 (finished inside the top 117).<br/> The player did not retain his European Tour card for 2023, but retained conditional status (finished between 118 and 155, inclusive).<br/> The player did not retain his European Tour card for 2023 (finished outside the top 155).