The 2021 CAF Women's Champions League COSAFA Qualifiers, commonly known as the 2021 COSAFA Women's Champions League, was the inaugural edition of the annual qualification competition for the CAF Women's Champions League organized by COSAFA for its nations. This edition was held in two stadiums in Durban, South Africa from 26 August to 4 September 2021.
The following teams participated in this edition of the competition. CD Costa do Sol from Mozambique had its license rejected by CAF for failing to meet the competition's criteria.
This edition of the tournament was held at the King Zwelithini Stadium and Moses Mabhida Stadium in Durban, South Africa.
Referees
Assistant Referees
The draw ceremony of the edition of the competition was held on 29 July 2021 11:00 CAT/SAST (09:00 UTC) in Johannesburg, South Africa.
Teams are ranked according to the three points for a win system (3 for a win, 1 for a draw and none/0 for a loss) and if tied on points, the following tie-breaking criteria are applied, in the order given, to determine the rankings.
All times are in South African Standard Time ().
<onlyinclude>
<onlyinclude></onlyinclude>
At the knockout stage, extra-time and penalty shoot-out may be used if necessary for tie-breakers if scores level after normal regulation time.