The 2021 Arizona Lottery 100 was a ARCA Menards Series West race held on November 6, 2021. It was contested over 100 laps on the oval. It was the ninth and final race of the 2021 ARCA Menards Series West season. Joe Gibbs Racing driver Ty Gibbs won his second race of the season. Jesse Love clinched the 2021 ARCA Menards Series West championship in a tie-breaker with Jake Drew.
Practice and qualifying were combined into 1 90-minute session, where the fastest lap counted as the driver's qualifying lap. Ty Gibbs collected the pole with a time of 26.654 and a speed of .