The 2021 African Handball Cup Winners' Cup was the 26th edition, organized by the African Handball Confederation, under the auspices of the International Handball Federation, the handball sport governing body. The tournament was held from 24 August till 2 September 2021 and took place in Meknes, Morocco, contested by 8 teams and won by Al Ahly SC of Egypt.
<small>* Note: Advance to quarter-finals</small>
<small>* Note: Advance to quarter-finals</small>
37TH MEN'S AND WOMEN'S AFRICAN CLUB CUP WINNERS CHAMPIONSHIPS