The 2021 Abu Dhabi Women's Tennis Open was a women's tennis tournament played on outdoor hard courts. It was the inaugural professional edition of the tournament and a WTA 500 tournament on the 2021 WTA Tour. It took place at the Zayed Sports City International Tennis Centre in Abu Dhabi, from 6 January to 13 January 2021. Fourth-seeded Aryna Sabalenka won the singles title.
The following players received entry using a protected ranking into the singles main draw:
The following player received entry as an alternate:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers:
The following pairs received entry into the doubles main draw using a protected ranking:
The following pairs received entry into the doubles main draw as alternates: