The 2021 AFL Women's draft consists of the various periods when the 14 clubs in the AFL Women's competition can recruit players prior to the competition's 2022 season 6.
In May 2021, just before the draft period began, the AFL Commission approved special draft and signing assistance to the , , , and to support the strengthening of their playing lists in line with the competition's leading clubs. As a condition of receiving assistance, the clubs were required to use at least five selections at the upcoming draft.
Players can be signed for one or two year contracts. The trade period opened on 31 May 2021 and will close on 9 June 2021. Players can be re-signed until 16 June 2021.
The delisted free agency period will close on 25 June 2021.
In the absence of a rookie draft, each club was permitted to sign players that had not played Australian rules football within the previous three years or been involved in an AFLW high-performance program.
Following final list lodgements, a number of players experienced changing circumstances that made them unable to participate in 2022 season 6. Clubs were granted permission to place these players on an inactive list, gaining end of draft selections to replace them for the one season. Players on each club's inactive list ahead of 2022 season 6 are listed below:
Where players were moved to inactive list after the draft had taken place, club were entitled to replace them by free agency signing.
Where multiple players were ruled unable to play due to COVID-19 related health and safety protocols, clubs were entitled to field up to five train on players to enable them to field a full side.