The 2020 season was Pakhtakor Tashkent's 29th season in the Uzbek League in Uzbekistan.
On 16 March, all football in Uzbekistan was suspended due to the COVID-19 pandemic in Uzbekistan.
On 20 July, the Uzbekistan Super League was suspended for a second time due to the COVID-19 pandemic in Uzbekistan, with it being announced on 24 July that the league would resume on 3 August with the scheduled 10th round matches.
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|- |colspan="14"|Players away on loan:
|- |colspan="14"|Players who left Pakhtakor Tashkent during the season: