The 2019 Open de Cagnes-sur-Mer Alpes-Maritimes was a professional tennis tournament played on outdoor clay courts. It was the twenty-second edition of the tournament which was part of the 2019 ITF Women's World Tennis Tour. It took place in Cagnes-sur-Mer, France between 6 and 12 May 2019.
The following players received wildcards into the singles main draw:
The following player received entry as a special exempt:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser: