The 2019 Nippon Professional Baseball (NPB) Draft was held on October 17, , for the 55th time at the Grand Prince Hotel Takanawa to assign amateur baseball players to the NPB. It was arranged with the special cooperation of Taisho Pharmaceutical with official naming rights. The draft was officially called "The Professional Baseball Draft Meeting supported by Lipovitan D ". It has been sponsored by Taisho Pharmaceutical for the seventh consecutive year since 2013.
Only the first round picks will be done by bid lottery. From 2015 to 2018, the second round of Waiver priority was given to the lowest team in the regular season of the league who the most wins in the Interleague play, but from 2019, the Professional Baseball Executive Committee has decided that the Central League and the Pacific League will be given waiver priority alternately every other year, and in 2019 Central League received the waiver priority. From the third round the order was reversed continuing in the same fashion until all picks were exhausted.