The 2018 SMU Mustangs women's soccer team represented Southern Methodist University during the 2018 NCAA Division I women's soccer season. The regular season began on August 16 and concluded on October 26. It was the program's 25th season fielding a women's varsity soccer team, and their 6th season in the AAC. The 2018 season was Chris Petrucelli's seventh year as head coach for the program.
|- !colspan=6 style=""| Non-conference regular season |-
|- !colspan=6 style=""| American Athletic Conference regular season |-
|- !colspan=6 style=""| American Athletic Conference Tournament |-
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