The 2018 Nicholls State Colonels football team represented Nicholls State University as a member of the Southland Conference during the 2018 NCAA Division I FCS football season. Led by fourth-year head coach Tim Rebowe, the Colonels compiled an overall record of 9âÂÂ4 with a mark of 7âÂÂ2 in conference play, sharing the Southland title with Incarnate Word. Nicholls State received the Southland's automatic bid to the NCAA Division I Football Championship, beating San Diego in the first round before losing to Eastern Washington in the second round. The team played home games at John L. Guidry Stadium in Thibodaux, Louisiana.
On July 12, 2018, the Southland announced their Preseason All-Conference Teams, with the Colonels having a conference leading 14 players selected.
Offense first team
Defense first team
Offense second team
On July 19, 2018, the Southland announced their preseason poll, with the Colonels predicted to finish in second place.