The 2018 Challenger Banque Nationale de Drummondville was a professional tennis tournament played on indoor hard courts. It was the 12th edition of the tournament and part of the 2018 ATP Challenger Tour, offering a total of $75,000 in prize money. It took place in Drummondville, Canada between March 13 and March 18, 2018.
The following players received wildcards into the singles main draw:
The following players entered the singles main draw with a protected ranking:
The following players received entry as alternates:
The following players received entry from the qualifying draw:
The following players received entry as lucky losers: