The 2017 AFC Champions League knockout stage was played from 22 May to 25 November 2017. A total of 16 teams competed in the knockout stage to decide the champions of the 2017 AFC Champions League.
The winners and runners-up of each of the eight groups in the group stage advanced to the round of 16, with both West Region (Groups AâÂÂD) and East Region (Groups EâÂÂH) having eight qualified teams.
<section begin=Format /> In the knockout stage, the 16 teams played a single-elimination tournament, with the teams split into the two regions until the final. Each tie was played on a home-and-away two-legged basis. The away goals rule, extra time (away goals would not apply in extra time) and penalty shoot-out were used to decide the winner if necessary (Regulations Article 11.3).<section end=Format />
The schedule of each round was as follows. Matches in the West Region were played on Mondays and Tuesdays, while matches in the East Region were played on Tuesdays and Wednesdays.
The bracket of the knockout stage was determined as follows:
<section begin=Bracket /> The bracket was decided after the draw for the knockout stage, which was held on 6 June 2017, 16:00 MYT (), at the JW Marriott Hotel Kuala Lumpur in Kuala Lumpur, Malaysia.
<section end=Bracket />
<section begin=Round of 16 /> In the round of 16, the winners of one group played the runners-up of another group from the same region, with the matchups determined by the group stage draw, and the group winners hosting the second leg.
|- |+West Region
|+East Region
<section end=Round of 16 />
Al-Ain won 6âÂÂ2 on aggregate.
Al-Ahli (KSA) won 4âÂÂ2 on aggregate.
Al-Hilal won 4âÂÂ2 on aggregate.
Persepolis won 1âÂÂ0 on aggregate.
Kawasaki Frontale won 7âÂÂ2 on aggregate.
2âÂÂ2 on aggregate. Guangzhou Evergrande won on away goals.
Shanghai SIPG won 5âÂÂ3 on aggregate.
Urawa Red Diamonds won 3âÂÂ2 on aggregate.
<section begin=Quarter-finals /> The draw for the quarter-finals was held on 6 June 2017. In the quarter-finals, the four teams from the West Region played in two ties, and the four teams from the East Region played in two ties, with the matchups and order of legs decided by draw, without any seeding or country protection.
|- |+West Region
|+East Region
<section end=Quarter-finals />
Al Hilal won 3âÂÂ0 on aggregate.
Persepolis won 5âÂÂ3 on aggregate.
5âÂÂ5 on aggregate. Shanghai SIPG won 5âÂÂ4 on penalties.
Urawa Red Diamonds won 5âÂÂ4 on aggregate.
<section begin=Semi-finals /> In the semi-finals, the two quarter-final winners from the West Region played each other, and the two quarter-final winners from the East Region played each other, with the order of legs determined by the quarter-final draw.
|- |+West Region
|+East Region
<section end=Semi-finals />
Al Hilal won 6âÂÂ2 on aggregate.
Urawa Red Diamonds won 2âÂÂ1 on aggregate.
<section begin=Final /> In the final, the two semi-final winners played each other, with the order of legs (first leg hosted by team from the West Region, second leg hosted by team from the East Region) reversed from the previous season's final.
Urawa Red Diamonds won 2âÂÂ1 on aggregate.<section end=Final />