The 2016 Sofia Open (also known as 2016 Garanti Koza Sofia Open for sponsorship reasons) was a men's tennis tournament played on indoor hard courts. It was the inaugural edition of the Sofia Open as part of the ATP World Tour 250 series of the 2016 ATP World Tour. It took place at the Arena Armeec in Sofia, Bulgaria, from 1 February until 7 February 2016. First-seeded Roberto Bautista Agut won the singles title.
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following pairs received wildcards into the doubles main draw: