The 2016 Copa Venezuela is the 47th edition of the competition. It began with the First Round on 28 June 2016, and concluded with the final on 19 October 2016. The winner will qualify for the 2017 Copa Sudamericana.
Venezuelan Primera División side Deportivo La Guaira were the defending champions after they beat Deportivo Lara 1âÂÂ0 on aggregate in the previous final in October 2015, but they were eliminated by Universidad Central in the second round. Zulia won the competition after defeating Estudiantes de Caracas 2âÂÂ0 on aggregate score in the final.
|- !colspan=5|Oriental Group
|- !colspan=5|Occidental Group
<small>Source:</small> <small>Soccerway</small>
|- !colspan=5|Oriental Group
|- !colspan=5|Occidental Group
<small>Source:</small> <small>Soccerway</small>
The first legs took place from 10 August 2016 to 28 August 2016, while the second legs took place from 24 August 2016 to 31 August 2016.
|- !colspan=5|Oriental Group
|- !colspan=5|Occidental Group
<small>Source:</small> <small>Soccerway</small>
The first legs were played on 4 September 2016, while the second legs took place on 7 September 2016.
|- !colspan=5|Oriental Group
|- !colspan=5|Occidental Group
<small>Source:</small> <small>Soccerway</small>
The first legs were played on 21 September 2016, with the second legs taking place on 5 October 2016.
|- !colspan=5|Oriental Group
|- !colspan=5|Occidental Group
<small>Source:</small> <small>Soccerway</small>
The first leg was played on 12 October 2016, with the second leg taking place on 19 October 2016.
<small>Source:</small> <small>Soccerway</small>