The 2016 Challenger Banque Nationale de Drummondville was a professional tennis tournament played on indoor hard courts. It was the 10th edition of the tournament and part of the 2016 ATP Challenger Tour, offering a total of $50,000 in prize money. It took place in Drummondville, Canada between March 14 and March 20, 2016.
The following players received wildcards into the singles main draw:
The following players received entry as alternates:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser: