The 2016 CAF Confederation Cup qualifying rounds were played from 12 February to 18 May 2016. A total of 59 teams competed in the qualifying rounds to decide the eight places in the group stage of the 2016 CAF Confederation Cup.
<section begin=Draw /> The draw for the preliminary, first and second rounds was held on 11 December 2015 in Dakar, Senegal.<section end=Draw />
The entry round of the 55 teams entered into the draw was determined by their performances in the CAF competitions for the previous five seasons (CAF 5-year ranking points shown in parentheses).
<section begin=Format /> In the qualifying rounds, each tie was played on a home-and-away two-legged basis. If the aggregate score was tied after the second leg, the away goals rule would be applied, and if still tied, extra time would not be played, and the penalty shoot-out would be used to determine the winner (Regulations III. 13 & 14).<section end=Format />
The schedule of each round was as follows.
<section begin=Bracket /> The eight winners of the second round advanced to the play-off round, where they were joined by the eight losers of the Champions League second round.<section end=Bracket />
The preliminary round included the 38 teams that did not receive byes to the first round. <section begin=Preliminary round />
<section end=Preliminary round />
1âÂÂ1 on aggregate. Vita Club Mokanda won 6âÂÂ5 on penalties.
Police won 4âÂÂ3 on aggregate.
Sagrada Esperança won 3âÂÂ2 on aggregate.
MC Oran won on walkover after Wallidan withdrew.
SC Gagnoa won 2âÂÂ0 on aggregate.
3âÂÂ3 on aggregate. Kawkab Marrakech won 5âÂÂ4 on penalties.
Bidvest Wits won 9âÂÂ0 on aggregate.
Renaissance won 3âÂÂ2 on aggregate.
Harare City won 6âÂÂ3 on aggregate.
2âÂÂ2 on aggregate. Stade Gabèsien won 4âÂÂ3 on penalties.
Nasarawa United won 2âÂÂ1 on aggregate.
Misr Lel Makkasa won 6âÂÂ1 on aggregate.
FC Saint-ÃÂloi Lupopo won 3âÂÂ1 on aggregate.
Al-Ittihad Tripoli won 5âÂÂ4 on aggregate.
0âÂÂ0 on aggregate. Deportivo Mongomo won 4âÂÂ2 on penalties.<br />The CAF announced on 2 March 2016 that UMS de Loum won on walkover after Deportivo Mongomo were disqualified for fielding an ineligible player.
SC Villa won 2âÂÂ0 on aggregate.
JKU won on walkover after Gaborone United withdrew.
Atlético Olympic won 2âÂÂ1 on aggregate.
Africa Sports won 4âÂÂ2 on aggregate.
The first round included 32 teams: the 19 winners of the preliminary round, and the 13 teams that received byes to this round. <section begin=First round />
<section end=First round />
Vita Club Mokanda won 1âÂÂ0 on aggregate.
Sagrada Esperança won 2âÂÂ1 on aggregate.
MC Oran won 4âÂÂ2 on aggregate.
Kawkab Marrakech won 3âÂÂ2 on aggregate.
Azam won 7âÂÂ3 on aggregate.
Espérance de Tunis won 7âÂÂ0 on aggregate.
Zanaco won 5âÂÂ2 on aggregate.
Stade Gabèsien won 2âÂÂ1 on aggregate.
CS Constantine won 4âÂÂ2 on aggregate.
Misr Lel Makkasa won 3âÂÂ2 on aggregate.
2âÂÂ2 on aggregate. Al-Ahly Shendi won on away goals.
Medeama won 2âÂÂ1 on aggregate.
FUS Rabat won 3âÂÂ2 on aggregate.
SC Villa won 5âÂÂ0 on aggregate.
CF Mounana won 5âÂÂ0 on aggregate.
ENPPI won 6âÂÂ1 on aggregate.
The second round included the 16 winners of the first round. <section begin=Second round />
<section end=Second round />
Sagrada Esperança won 4âÂÂ1 on aggregate.
Kawkab Marrakech won 1âÂÂ0 on aggregate.
Espérance de Tunis won 4âÂÂ2 on aggregate.
Stade Gabèsien won 4âÂÂ1 on aggregate.
Misr Lel Makkasa won 3âÂÂ2 on aggregate.
Medeama won 2âÂÂ0 on aggregate.
FUS Rabat won 7âÂÂ1 on aggregate.
2âÂÂ2 on aggregate. CF Mounana won 5âÂÂ4 on penalties.
The play-off round included 16 teams: the eight winners of the Confederation Cup second round and the eight losers of the Champions League second round. <section begin=Play-off round /> The draw for the play-off round was held on 21 April 2016, 14:00 EET (), at the CAF Headquarters in Cairo, Egypt. The winners of the Confederation Cup second round were drawn against the losers of the Champions League second round, with the former hosting the second leg.<noinclude>
The 16 teams were seeded by their performances in the CAF competitions for the previous five seasons (CAF 5-year ranking points shown in parentheses):
First, a team from Pot A and a team from Pot B were drawn into two ties. Next, a team from Pot C and a team from Pot D were drawn into two ties. Finally, the remaining teams from Pot B and Pot D were drawn into the last four ties.
</noinclude> The eight winners of the play-off round advanced to the group stage.
<section end=Play-off round />
1âÂÂ1 on aggregate. MO Béjaïa won on away goals.
FUS Rabat won 4âÂÂ0 on aggregate.
ÃÂtoile du Sahel won 2âÂÂ1 on aggregate.
2âÂÂ2 on aggregate. TP Mazembe won on away goals.
1âÂÂ1 on aggregate. Al-Ahli Tripoli won on away goals.
Kawkab Marrakech won 2âÂÂ1 on aggregate.
Young Africans won 2âÂÂ1 on aggregate.
3âÂÂ3 on aggregate. Medeama won on away goals.<br />The CAF announced on 24 May 2016 that Mamelodi Sundowns won their Champions League second round tie on walkover after AS Vita Club were disqualified for fielding an ineligible player in their preliminary round tie against Mafunzo. Mamelodi Sundowns played in the Confederation Cup play-off round before they were reinstated to the Champions League.