2014 Regional League Division 2 North Eastern Region is the 6th season of the League competition since its establishment in 2009. It is in the third tier of the Thai football league system. The league winners and runners up will qualify for the 2014 Regional League Division 2 championship stage.
Roi Et United were promoted to the 2014 Thai Division 1 League.
Yasothon United have withdrawn from the 2014 campaign.