The elimination phase of the 2014 Copa Sudamericana was played from August 19 to September 24, 2014. A total of 46 teams competed in the elimination phase.
The draw of the tournament was held on May 20, 2014, 12:00 , at the Sheraton Hotel in Buenos Aires, Argentina.
Excluding the defending champion (entering in the round of 16), the other 46 teams were divided into four zones:
The draw mechanism was as follows:
The following was the seeding of the 46 teams entered into the first stage and second stage draw:
In the elimination phase, each tie was played on a home-and-away two-legged basis. If tied on aggregate, the away goals rule was used. If still tied, the penalty shoot-out was used to determine the winner (no extra time was played). The 15 winners of the second stage (three from Argentina Zone, four from Brazil Zone, eight from ties between South Zone and North Zone) advanced to the round of 16 to join the defending champion (Lanús).
The first legs were played on August 19âÂÂ21, and the second legs were played on August 26âÂÂ28, 2014.
|- !colspan=6|South Zone
|- !colspan=6|North Zone
Huachipato won 6âÂÂ3 on aggregate.
Universitario won 2âÂÂ1 on aggregate.
Deportivo Capiatá won 5âÂÂ3 on aggregate.
Cerro Porteño won 2âÂÂ1 on aggregate.
General DÃÂaz won 4âÂÂ3 on aggregate.
Libertad won 3âÂÂ1 on aggregate.
River Plate won 4âÂÂ0 on aggregate.
Peñarol won 6âÂÂ0 on aggregate.
Caracas won 2âÂÂ0 on aggregate.
Barcelona won 3âÂÂ0 on aggregate.
Atlético Nacional won 2âÂÂ1 on aggregate.
Emelec won 3âÂÂ2 on aggregate.
Deportivo Cali won 3âÂÂ0 on aggregate.
Universidad César Vallejo won 4âÂÂ3 on aggregate.
Independiente del Valle won 2âÂÂ1 on aggregate.
Tied 2âÂÂ2 on aggregate, Universidad Católica won on penalties.
The first legs were played on August 27âÂÂ28, September 3âÂÂ4, 10âÂÂ11, and 16âÂÂ18, and the second legs were played on September 3âÂÂ4, 16âÂÂ18, and 23âÂÂ25, 2014.
Vitória won 3âÂÂ1 on aggregate.
Deportivo Capiatá won 4âÂÂ2 on aggregate.
River Plate won 3âÂÂ0 on aggregate.
Huachipato won 2âÂÂ1 on aggregate.
Tied 2âÂÂ2 on aggregate, Goiás won on away goals.
Peñarol won 3âÂÂ2 on aggregate.
Universidad César Vallejo won 5âÂÂ2 on aggregate.
Bahia won 3âÂÂ1 on aggregate.
Cerro Porteño won 3âÂÂ1 on aggregate.
Estudiantes won 1âÂÂ0 on aggregate.
Emelec won 3âÂÂ2 on aggregate.
São Paulo won 3âÂÂ2 on aggregate.
Libertad won 2âÂÂ1 on aggregate.
Boca Juniors won 4âÂÂ1 on aggregate.
Tied 3âÂÂ3 on aggregate, Atlético Nacional won on away goals.