The 2013 Colorado Buffaloes football team represented the University of Colorado at Boulder during the 2013 NCAA Division I FBS football season. Led by first-year head coach Mike MacIntyre, the Buffaloes played their home games on-campus at Folsom Field in Boulder and were members of the Pac-12 Conference. Head coach Mike MacIntyre was hired after the firing of Jon Embree concluding the 2012 season.
National Signing Day was on February 6, 2013, and Colorado signed high school athletes from around the country.
Colorado's game vs Fresno State on September 14 was canceled due to flooding, making Colorado need to add a 12th game. On September 30, Charleston Southern was granted a waiver to play a 13th regular season game to be able to play Colorado.