The second stage of the 2012 Copa Santander Libertadores de América ran from February 7 to April 19, 2012 (match days: February 7âÂÂ9, 14âÂÂ16, 21âÂÂ23, March 6âÂÂ8, 13âÂÂ15, 20âÂÂ22, 27âÂÂ29, April 3âÂÂ5, 10âÂÂ12, 17âÂÂ19).
Twenty-six teams qualified directly into this round, to be joined by the six winners of the first stage. The thirty-two teams were drawn into eight groups of four on November 25, 2011, in Asunción.
The teams in each group played each other in a double round-robin format, playing the other teams in the group once at home and once away. Each team earned 3 points for a win, 1 point for a draw, and 0 points for a loss. The following criteria were used for breaking ties on points:
The top two teams from each group advanced to the round of 16.
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