The 2012 CAF Champions League knock-out stage matches took place between October and November 2012. The matches were held from 5âÂÂ7 October (semifinals first leg), 19âÂÂ21 October (semifinals second leg), 2âÂÂ4 November (final first leg) and 16âÂÂ18 November (final second leg).
All knock-out ties were decided over two legs, with aggregate goals used to determine the winner. If the sides were level on aggregate after the second leg, the away goals rule applied, and if still level, the tie proceeded directly to a penalty shootout (no extra time is played).
The knock-out stage featured four teams: the two group winners and the two group runners-up from the group stage. In the semi-finals, the group A winners played the group B runners-up, and the group B winners played the group A runners-up. In both ties, the group winners hosted the second leg at home.
ES Tunis won 1âÂÂ0 on aggregate and advanced to the 2012 CAF Champions League Final.
Al-Ahly won 4âÂÂ3 on aggregate and advanced to the 2012 CAF Champions League Final.
Al-Ahly won 3âÂÂ2 on aggregate.