2011 Regional League Division 2 Northern Region is the third season of the League competition since its establishment in 2009. It is in the third tier of the Thai football league system. The league winners and runners up will qualify for the 2011 Regional League Division 2 championship stage.
Chiangmai and Chainat were promoted to the 2011 Thai Division 1 League.
Lamphun Warrior and Nan joined the newly expanded league setup.
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