The 2011 S.League was the 16th season of the S.League, the top professional football league in Singapore. Tampines Rovers FC won their third title. As in the previous season the S.League was not allowed to send a team to the AFC Champions League because of the participation of a foreign team in the league.
Beijing Guoan Talent withdrew their participation in the league after just one season. They were replaced by Tanjong Pagar United, who returned to the highest football league of Singapore after a seven-year absence. The club will be based at Clementi Stadium.
In further changes, Sengkang Punggol were renamed to Hougang United. Moreover, Home United moved back to Bishan Stadium after splitting their previous season home matches between Clementi Stadium and Jalan Besar Stadium.
Each club is allowed to have up to a maximum of 4 foreign players.
<onlyinclude></onlyinclude>
Every team will play the other teams a total of three times, either twice at home and once away or vice versa, for a total of 33 matches per team.