The 2011 Big 12 Conference football season was the 16th season for the Big 12, as part of the 2011 NCAA Division I FBS football season. It had 10 football teams due to the departure of Colorado to the Pac-12 and Nebraska to the Big Ten. It was also the last Big 12 season for Texas A&M and Missouri, as both of them departed for the SEC in July 2012.
The Big 12 preseason prediction poll, as voted on by members of the media, was released on July 20, 2011.