The 2010 UAB Blazers football team represented the University of Alabama at Birmingham (UAB) as a member of the East Division in Conference USA (C-USA) during the 2010 NCAA Division I FBS football season. Led by fourth-year head coach Neil Callaway, the Blazers compiled an overall record of 4âÂÂ8 with a mark of 3âÂÂ5 in conference play, placing fifth in C-USA's East Division. The team played home games at Legion Field in Birmingham, Alabama.