The 2010 Mnet Asian Music Awards took place on November 28, 2010, at The Venetian Macao in Macau, China. It is the first ceremony to take place outside of South Korea with approximately 10,000 people attending the show. 2NE1 won the most awards, winning four out of their six nominations, including Artist of the Year and Album of the Year.
The ceremony marked the twelfth edition of the annual music awards. The ceremony's slogan was "One Asia". It was broadcast live in China, Japan, Hong Kong and Southeast Asia through various channels, as well as in the United States and Canada.
Artists Taeyang, DJ Doc, Gummy, Rain, Hot Potato, Far East Movement, Perfume, I Me, and Chemistry all won awards during the televised broadcast. Recorded videos of international artists were shown including Lam Tun, Ho Gu Hua, Hong Ying, Pam Tan, Keri Hilson, and will.i.am. CNBLUE, 2AM, Jo Kwon, Gain also won awards but were not shown on broadcast due to their absence.
The following individuals and groups, listed in order of appearance, performed musical numbers at the ceremony.
Winners are listed first and highlighted in boldface.
The following artist(s) received two or more wins (excluding the special awards):
The following artist(s) received more than two nominations:
SM Entertainment boycotted the 2010 Mnet Asian Music Awards, as they did in 2009, due to issues with fairness and employing a "no show, no award" policy where the winner must attend the ceremonies.
In addition, Mnet came under criticism due to the date and location of the awards. It was the first Mnet Asian Music Awards to take place outside of South Korea. They also aired on a Sunday, which means performers had to choose between SBS's The Music Trend show or the awards ceremony.