The 2010 Michigan Senate elections were held on November 2 of that year, with partisan primaries to determine each party's nominees on August 3. The election was the last contested under constituency boundaries drawn as a result of the 2000 U.S. census, and members served in the 96th and 97th Legislatures.
State Senators are only allowed to serve two four-year terms, a maximum of eight years. The following Senators were not eligible to run for a new term in 2010:
All results below are from the certified election results posted by the secretary of state.
State Senator John Gleason resigned his seat to accept election as the Genesee County Clerk. This triggered a by-election, which was held May 7, 2013. Jim Ananich won the special election with 75.27% of the vote.