The 2007 Campeonato Nacional Apertura Copa Banco del Estado was the 81st Chilean League top flight tournament, in which Colo-Colo won its 26th league title.
<onlyinclude></onlyinclude> <small>Rules for classification: 1st points; 2nd wins; 3rd goal difference; 4th goals scored; 5th away goals; 6th red cards; 7th yellow cards; 8th draw.</small>
<small>Audax Italiano & Colo-Colo qualified for the 2007 Copa Sudamericana</small>