The 2006 NCAA National Collegiate Women's Ice Hockey Tournament involved eight schools playing in single-elimination play to determine the national champion of women's NCAA Division I college ice hockey. It began on March 17, 2006, and ended with the championship game on March 26. The quarterfinals were conducted at the homes of the teams considered to be higher seeds, although no seed was given for either team in two of the games. The Frozen Four was conducted in Minneapolis. A total of seven games were played. Jessie Vetter was named the Most Outstanding Player to become the first goaltender to win the honor.
The winners of the ECAC, WCHA, and Hockey East tournaments all received automatic berths to the NCAA tournament. The other five teams were selected at-large. The top two teams were then seeded, and four teams received home ice for the quarterfinals.
<nowiki>*</nowiki> Most Outstanding Player