The 2006 Lafayette Leopards football team represented Lafayette College as member of the Patriot League during the 2006 NCAA Division I FCS football season. Led by seventh-year head coach Frank Tavani, the Leopards compiled an overall record of 6âÂÂ6 with a mark of 5âÂÂ1 in conference play, sharing the Patriot League title with Lehigh. Lafayette advanced to the NCAA Division I Football Championship playoffs, where the Leopards lost in the first round to UMass. Lafayette played home games at Fisher Field in Easton, Pennsylvania.
Before the first home game of 2006, Lafayette renovated the football team's longtime home stadium, Fisher Field. All games were broadcast on the Lafayette Sports Network (LSN).