The 2006 Cork Premier Intermediate Football Championship was the inaugural staging of the Cork Premier Intermediate Football Championship since its establishment by the Cork County Board. The draw for the opening round fixtures took place on 11 December 2005. The championship began on 8 April 2006 and ended on 26 November 2006.
The final was contested between St. Vincent's and Glanmire at Páirc UàRinn in Cork. After two replays, St. Vincent's won the title by 1-05 to 0-07 to claim their first championship title in the grade and a first title in any grade since 1968.
Glanmire's James Murphy was the championship's top scorer with 0-39.