The 2005 Kilkenny Senior Hurling Championship was the 111th staging of the Kilkenny Senior Hurling Championship since its establishment by the Kilkenny County Board.
James Stephens were the defending champions.
On 2 October 2005, Glenmore were relegated after a 2âÂÂ11 to 0âÂÂ15 defeat by Fenians.
On 23 October 2005, James Stephens won the title after a 1âÂÂ18 to 2âÂÂ12 defeat of Ballyhale Shamrocks in the final at Nowlan Park. It was their eighth championship title overall and their second title in succession.
Eoin Larkin from the James Stephens club was the championship's top scorer with 0-25.
Promoted from the Kilkenny Intermediate Hurling Championship
Relegated to the Kilkenny Intermediate Hurling Championship