The 2001 Oklahoma State Cowboys football team represented Oklahoma State University as a member of the Big 12 Conference during the 2001 NCAA Division I-A football season. Led by first-year head coach Les Miles, the Cowboys compiled an overall record of 4âÂÂ7 with a mark of 2âÂÂ6 in conference play, placing fifth in the Big 12's South Division. Oklahoma State played home games at Lewis Field in Stillwater, Oklahoma.
In the final game of the season, the Cowboys, amidst a losing campaign, went to Norman, Oklahoma and upset their in-state rivals, the Oklahoma Sooners, who were contenting for a national championship.
No one from the Cowboys was selected in the 2002 NFL draft. Kevin Williams was selected ninth overall in the 2003 NFL draft. Rashaun Woods (31st overall), Tatum Bell (41st overall), and Antonio Smith (135th overall) were selected in the 2004 NFL draft. Linebacker Dwayne Levels was not selected in an NFL draft, but played one season in the league. Darrent Williams, a true freshman starter at cornerback, was drafted in the second round (56th overall) of the 2005 NFL draft. Billy Bajema, a freshman tight end, was selected in the seventh round of the 2005 NFL draft.