The 2001 Cork Senior Football Championship was the 113th staging of the Cork Senior Football Championship since its establishment by the Cork County Board in 1887. The draw for the opening fixtures took place on 10 December 2000. The championship began on 14 April 2001 and ended on 30 September 2001.
Nemo Rangers entered the championship as the defending champions.
On 30 September 2001, Nemo Rangers won the championship following a 1-14 to 0-06 defeat of Bantry Blues in the final. This was their 12th championship title overall and their second title in succession.
Promoted from the Cork Intermediate Football Championship