The 2000 Sta. Lucia Realtors season was the 8th season of the franchise in the Philippine Basketball Association (PBA).
Under new head coach Norman Black, who moved from Pop Cola to Sta.Lucia at the beginning of the season, the Realtors played in the PBA championship series for the first time in their eight-year history during the Commissioner's Cup, Sta.Lucia lost to defending champions San Miguel Beermen in five games.
<sub>(*) loss was reversed and change to a win</sub>