The 2000 NCAA Division I Cross Country Championships were the 62nd annual NCAA Men's Division I Cross Country Championship and the 20th annual NCAA Women's Division I Cross Country Championship to determine the team and individual national champions of NCAA Division I men's and women's collegiate cross country running in the United States. In all, four different titles were contested: men's and women's individual and team championships.
Held on November 20, 2000, the combined meet was hosted by Iowa State University in Ames, Iowa. The distance for the men's race was while the distance for the women's race was . This championship was one of the coldest on record with winds holding wind chills around at race time.
The men's team championship was won by Arkansas (83 points), the Razorbacks' third consecutive and eleventh overall. The women's team championship was won by Colorado (117 points), the Buffaloes' first.
The two individual champions were, for the men, Keith Kelly (Providence, 30:14.5) and, for the women, Kara Grgas-Wheeler (Colorado, 20:30.5).