In enzymology, 2-aminomuconate deaminase () (also known as amnd) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are 2-aminomuconate and H<sub>2</sub>O, whereas its two products are 4-oxalocrotonate and NH<sub>3</sub>.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in compounds that have not been otherwise categorized within EC number 3.5. The systematic name of this enzyme class is 2-aminomuconate aminohydrolase. This enzyme participates in tryptophan metabolism.