2-amino-4-deoxychorismate synthase (, ADIC synthase, 2-amino-2-deoxyisochorismate synthase, SgcD) is an enzyme with systematic name (2S)-2-amino-4-deoxychorismate:2-oxoglutarate aminotransferase. This enzyme catalyses the following chemical reaction
This reaction is an early part of the biosynthesis of the benzoxazolinate fragment of the enediyne antitumour antibiotic C-1027 from Streptomyces globisporus. 2-amino-2-deoxyisochorismic acid is produced from chorismic acid by transamination using glutamine as the source of the amino group:
The enzyme requires Mg<sup>2+</sup>.