2-alkenal reductase

In enzymology, a 2-alkenal reductase () is an enzyme that catalyzes the chemical reaction

The three substrates of this enzyme are n-alkanal, NAD⁺, and NADP⁺, whereas its four products are alk-2-enal, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is n-alkanal:NAD(P)+ 2-oxidoreductase. Other names in common use include NAD(P)H-dependent alkenal/one oxidoreductase, and NADPH:2-alkenal alpha,beta-hydrogenase.

Structural studies

As of late 2007, three structures have been solved for this class of enzymes, with PDB accession codes , , and .

References