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2-Picolylamine

2-Picolylamine is an organic compound with the formula H<sub>2</sub>NCH<sub>2</sub>C<sub>5</sub>H<sub>4</sub>N. A colorless liquid, it is a common bidentate ligand and a precursor to more complex multidentate ligands such as tris(2-pyridylmethyl)amine. It is usually prepared by hydrogenation of 2-cyanopyridine. One such complex is Baratta's catalyst RuCl<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>(ampy) (ampy = 2-picolylamine) for transfer hydrogenation. Salts of the complex [Fe(pyCH<sub>2</sub>NH<sub>2</sub>)<sub>3</sub>]<sup>2+</sup> exhibit spin crossover behavior, whereby the complex switches from high to low spin configurations, depending on the temperature.

Safety

The oral in quail is low, being 750 mg/kg.

References