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2-Fluoronitrobenzene

2-Fluoronitrobenzene is an organic compound with the formula FC<sub>6</sub>H<sub>4</sub>NO<sub>2</sub>. It is one of three isomeric fluoronitrobenzenes. A colorless liquid, it is prepared from 2-nitrochlorobenzene using the Halex process:

Applications

2-Fluoronitrobenzene has application in the synthesis of Amoxapine, Olanzapine, an early synthesis of J-113,397, Deschloroclozapine, and 11-Piperazinyl-dibenz[b,f][1,4]oxazepane [21636-40-8].

The closely related compound, 2-chloronitrobenzene is used in the synthesis of quetiapine.

References