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2,4-Dichlorobenzoyl-CoA reductase

In enzymology, a 2,4-dichlorobenzoyl-CoA reductase () is an enzyme that catalyzes the chemical reaction

4-chlorobenzoyl-CoA + NADP<sup>+</sup> + HCl 2,4-dichlorobenzoyl-CoA + NADPH + H<sup>+</sup>

The 3 substrates of this enzyme are 4-chlorobenzoyl-CoA, NADP<sup>+</sup>, and HCl, whereas its 3 products are 2,4-dichlorobenzoyl-CoA (the thioester of 2,4-dichlorobenzoic acid), NADPH, and H<sup>+</sup>.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 4-chlorobenzoyl-CoA:NADP+ oxidoreductase (halogenating). This enzyme participates in degradation of 2,4-dichlorobenzoate.

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