The 1988 United States Senate election in Maryland was held on November 8, 1988. Incumbent Democratic U.S. Senator Paul Sarbanes was reelected to a third term in a landslide. As in 1982, Sarbanes won strongly Republican Garrett County, which has never supported a Democratic presidential candidate and has not voted Democratic in a Senate election since this election. This is the last time that Maryland voted for a Senate candidate and a presidential candidate of different political parties.