The 1988 Eagle Pro Box Lacrosse League season is the 2nd season of the Eagle Pro Box Lacrosse, that began on January 3, 1988, and concluded with the championship game on March 20. On May 15, 1988 the league was renamed Major Indoor Lacrosse League (MILL), a name the league would keep for the next ten years.
No teams were added, removed, or relocated for the 1988 season.
Bold numbers indicate new single-season records. Italics indicate tied single-season records.