The 1981 Tipperary Senior Hurling Championship was the 91st staging of the Tipperary Senior Hurling Championship since its establishment by the Tipperary County Board in 1887.
Roscrea were the defending champions.
On 25 October 1981, Borris-Ileigh won the championship after a 1âÂÂ14 to 0âÂÂ12 defeat of Roscrea in the final at Semple Stadium. It was their fourth championship title overall and their first title since 1953.