The 1981 Antrim Senior Hurling Championship was the 81st staging of the Antrim Senior Hurling Championship since its establishment by the Antrim County Board in 1901. The championship ran from 9 August to 3 October 1981.
McQuillan Ballycastle entered the championship as the defending champions.
The final, a replay, was played on 3 October 1981 at Fr Healy Park in Loughguile, between RuairàÃÂg, Cushendall and McQuillan Ballycastle, in what was their third consecutive meeting in the final. RuairàÃÂg, Cushendall won the match by 3âÂÂ08 to 0âÂÂ16 to claim their first ever championship title.