The 1980-81 KNVB Cup 63rd edition of the Dutch national football annual knockout tournament for the KNVB Cup. 46 teams contested, beginning on 6 September 1980 and ending at the final on 28 May 1981.
AZ from Alkmaar (at the time called AZ'67) beat Ajax 3âÂÂ1 and won the cup for the second time.
During the quarter and semi-finals, two-legged matches were held.
The matches of the first round were played on 6-7 September 1980.
<sub>1</sub> Eerste Divisie; <sub>A</sub> Amateur teams
The matches of the second round were played on November 15 and 16, 1980. The Eredivisie clubs entered the tournament here.
<sub>E</sub> Eredivisie
The matches of the round of 16 were played on January 24 and 25, 1981.
The quarter finals were played on February 25 and April 1, 1980.
The semi-finals were played on April 14 and May 12, 1980.
AZ also won the Dutch Eredivisie championship, thereby taking the double. They would participate in the European Cup, so finalists Ajax could play in the Cup Winners' Cup.