The 1978 Brisbane Rugby League premiership was the 71st season of Brisbane's professional rugby league football competition. Eight teams from across Brisbane competed for the premiership, which culminated in a grand final match between the Eastern Suburbs and Fortitude Valley clubs.
Teams played each other three times, with 21 rounds of competition played. It resulted in a top four of Eastern Suburbs, Redcliffe, Western Suburbs and Fortitude Valley.
Eastern Suburbs 14 (Tries: R. Morris, G. Holben. Goals: G. McDonald 3, W. Lindenburg.)
Fortitude Valley 10 (Tries: V. Wieland, M. Neill. Goals: M. Neill, A. Mills.)